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Autologous chondrocyte implantation (ACI) has been used in adults with deep cartilage defects for over 30 years and has been further developed and modified over time. For the most recent procedure, matrix-induced ACI (M-ACI), favorable effects have been shown suggesting that the benefits are at least comparable to those of therapy alternatives. No advantages are evident for the other two older procedures, collagen-covered ACI (ACI-C) and ACI with a periosteal flap (ACI-P).

Source: Medical Xpress

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